Andreessen Horowitz is doubling down on crypto again. The venture capital giant unveiled its Crypto Fund 5 with $2.2 billion in committed capital, according to a company spokesperson.
The fund will back crypto entrepreneurs at all stages over a ten-year deployment period. The firm is focusing on founders building practical applications on top of crypto infrastructure, particularly in payments, financial services, and decentralized systems.
$2.2B Focus: Durable Infrastructure Beyond the Hype
The new vehicle is roughly half the size of its fourth fund, which raised $4.5 billion in 2023, but still dwarfs recent peers. Former a16z partner-led Huan Ventures raised just $1 billion, and Dragonfly Capital secured $650 million. Partners at a16z see the current quieter market as fertile ground for lasting value.
“We’re at one of those quieter moments now. And the signal coming through is one of the most encouraging it has been in years,” they wrote in a blog post Tuesday. The fund targets founders who “are working on the part of the cycle that gets less attention and produces more of the lasting value: turning new infrastructure into products people use every day.”
Stablecoins, Perps, and Tokenized Assets in Focus
Several verticals are showing “meaningful growth.” The stablecoin market has ballooned to $320 billion in market cap, with adoption continuing through downturns for cross-border payments, savings, and daily transactions. a16z highlighted that legacy systems are “slow, expensive, and unreliable,” giving stablecoins a clear edge.
Other areas include perpetual futures, blockchain-based lending, prediction markets, and tokenized real-world assets. These products have already achieved product-market fit, the firm argues; now the goal is scaling.
AI Meets Crypto: A Pivotal Coordination Layer
As venture capital floods into AI startups, a16z sees crypto’s role as the financial and coordination layer for AI systems becoming more critical. “Software is getting more complex and harder to trust. AI systems are powerful and largely opaque. The infrastructure the internet runs on is more consolidated than ever. In that environment, the properties that crypto networks were designed to provide become more valuable, not less,” the blog stated.
The firm plans to back projects that leverage crypto to solve trust and coordination problems in AI. Despite the market being far from the 2021 frenzy, a spokesperson said: “We believe while sentiment may be low, the fundamentals of the crypto industry are at an all-time high.”

