US-Iran talks in Islamabad, Pakistan lasted 21 hours and ended without an agreement. After the outcome became public, Bitcoin dropped 2% within 30 minutes and fell below $72,000.
Washington says its “final and best” offer is on the table
US Vice President JD Vance told reporters after the meeting that the US side had left behind what he described as a simple proposal, calling it Washington’s “final and best” offer. He said the next move now rests with Tehran. In his account, the central dispute remains the definition and limits tied to nuclear weapons.
Vance said Iran has repeatedly claimed it does not intend to build an atomic bomb, but the US wants a clearer commitment. He said Washington needs guarantees that Iran will neither seek nuclear weapons nor pursue the technology and equipment that could let it obtain them quickly. He added that the US has not yet seen that commitment, though it still holds out hope.
Tehran says one meeting was never expected to settle everything
Iranian Foreign Ministry spokesman Esmaeil Baqaei told the state news agency that the talks came after a war that lasted 40 days and opened in an atmosphere of distrust and suspicion. For that reason, he said, there was never an expectation that a single meeting would produce a final deal.
Baqaei said Iran will keep working to narrow the gap between the two sides. After news of the talks reached Tehran, people discussed the outlook through social media and text messages. The report said many Iranians have been following the negotiations closely, hoping a diplomatic breakthrough could both end the fighting and bring economic relief if sanctions are lifted.
Crypto market reacts to stalled negotiations
The lack of progress quickly fed into market prices. Bitcoin lost the $72,000 level in short-term trading, showing that geopolitical headlines are still moving crypto markets. The reaction came as traders watched for any fresh signal from either side on the proposal and on the path of future talks.

