Moderna, not an AI-linked chipmaker, has become the best-performing stock in the S&P 500 so far in 2026, according to Techub, citing BeInCrypto. The vaccine maker’s shares have climbed more than 600% this year and closed at $225 last Friday. The rally was tied to late-stage trial results for its experimental cancer vaccine.
The surge also pushed Moderna back into the Nasdaq-100 Index. More than 200 funds tracking that benchmark, with over $800 billion in assets under management, are required to buy the stock. Moderna and Merck said on Aug. 19 that their experimental cancer vaccine passed a final-stage trial in melanoma patients, though detailed results have not yet been released.
Investors are expected to get the full trial data on Oct. 24 at a major cancer conference in Madrid. Not everyone is convinced the move can hold. Former pharmaceutical executive Martin Shkreli said Moderna’s stock bubble could burst within the next six months.
Moderna has emerged as the best-performing member of the S&P 500 so far in 2026, even as the broader U.S. equity market has been dominated by the AI trade, according to Techub, citing BeInCrypto.
The COVID-19 vaccine maker’s stock is up more than 600% this year and closed at $225 last Friday. The gain was linked to late-stage trial results for its experimental cancer vaccine.
The rally has also returned Moderna to the Nasdaq-100 Index. More than 200 funds that track the index, with more than $800 billion in assets under management, are required to buy the stock.
Moderna and Merck announced on Aug. 19 that their experimental cancer vaccine had passed a final-stage trial in melanoma patients, although detailed results have not yet been disclosed.
Investors are set to receive the full trial data on Oct. 24 at a major cancer conference in Madrid.
Not all investors are bullish on the run-up. Former pharmaceutical executive Martin Shkreli said Moderna’s stock bubble could burst within the next six months.
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